ACCF/ACG/AHA 2010 expert consensus document on the concomitant use of proton pump inhibitors and thienopyridines: a focused update of the ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use

Neena S Abraham; Mark A Hlatky; Elliott M Antman; Deepak L Bhatt; David J Bjorkman; Craig B Clark; Curt D Furberg; David A Johnson; Charles J Kahi; Loren Laine; Kenneth W Mahaffey; Eamonn M Quigley; James Scheiman; Laurence S Sperling; Gordon F Tomaselli; ACCF/ACG/AHA

doi:10.1038/ajg.2010.445

ACCF/ACG/AHA 2010 expert consensus document on the concomitant use of proton pump inhibitors and thienopyridines: a focused update of the ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use

Am J Gastroenterol. 2010 Dec;105(12):2533-49. doi: 10.1038/ajg.2010.445.

Authors

Neena S Abraham, Mark A Hlatky, Elliott M Antman, Deepak L Bhatt, David J Bjorkman, Craig B Clark, Curt D Furberg, David A Johnson, Charles J Kahi, Loren Laine, Kenneth W Mahaffey, Eamonn M Quigley, James Scheiman, Laurence S Sperling, Gordon F Tomaselli; ACCF/ACG/AHA

Collaborators

ACCF/ACG/AHA:
Eric R Bates, Deepak L Bhatt, Victor A Ferrari, John D Fisher, Timothy J Gardner, Federico Gentile, Mark A Hlatky, Alice K Jacobs, Sanjay Kaul, David J Moliterno, Howard H Weitz, Deborah J Wesley

PMID: 21131924
DOI: 10.1038/ajg.2010.445

No abstract available

Publication types

Practice Guideline
Review

MeSH terms

Anti-Inflammatory Agents, Non-Steroidal / administration & dosage*
Anti-Inflammatory Agents, Non-Steroidal / adverse effects*
Anti-Inflammatory Agents, Non-Steroidal / metabolism
Aryl Hydrocarbon Hydroxylases / metabolism
Aspirin / administration & dosage
Aspirin / adverse effects
Aspirin / metabolism
Cardiovascular Diseases / drug therapy
Clopidogrel
Cytochrome P-450 CYP2C19
Drug Interactions
Drug Therapy, Combination
Gastrointestinal Hemorrhage / chemically induced*
Gastrointestinal Hemorrhage / prevention & control
Histamine H2 Antagonists / administration & dosage*
Histamine H2 Antagonists / adverse effects*
Histamine H2 Antagonists / metabolism
Humans
Piperazines / administration & dosage
Piperazines / adverse effects
Piperazines / metabolism
Platelet Aggregation Inhibitors / administration & dosage*
Platelet Aggregation Inhibitors / adverse effects*
Platelet Aggregation Inhibitors / metabolism
Prasugrel Hydrochloride
Proton Pump Inhibitors / administration & dosage*
Proton Pump Inhibitors / adverse effects*
Proton Pump Inhibitors / metabolism
Purinergic P2Y Receptor Antagonists / administration & dosage*
Purinergic P2Y Receptor Antagonists / adverse effects*
Purinergic P2Y Receptor Antagonists / metabolism
Risk Factors
Thienopyridines / administration & dosage*
Thienopyridines / adverse effects*
Thienopyridines / metabolism
Thiophenes / administration & dosage
Thiophenes / adverse effects
Thiophenes / metabolism
Ticlopidine / administration & dosage
Ticlopidine / adverse effects
Ticlopidine / analogs & derivatives*
Ticlopidine / metabolism

Substances

Anti-Inflammatory Agents, Non-Steroidal
Histamine H2 Antagonists
Piperazines
Platelet Aggregation Inhibitors
Proton Pump Inhibitors
Purinergic P2Y Receptor Antagonists
Thienopyridines
Thiophenes
Clopidogrel
Aryl Hydrocarbon Hydroxylases
CYP2C19 protein, human
Cytochrome P-450 CYP2C19
Prasugrel Hydrochloride
Ticlopidine
Aspirin