Dopamine: helping males copulate for at least 200 million years: theoretical comment on Kleitz-Nelson et al. (2010)

Behav Neurosci. 2010 Dec;124(6):877-80; discussion 881-3. doi: 10.1037/a0021823.


Brain dopamine (DA) systems are implicated in a variety of behavioral responses and clinical syndromes, including sex, drug addiction, feeding, satiety, sleep, wakefulness, arousal, attention, reward, decision-making, depression, anxiety, psychosis, and movement disorders. The paper in this issue by Kleitz-Nelson, Dominguez, and Ball (2010) shows how DA release in the medial preoptic area of male quail are activated in an androgen-dependent manner during appetitive and consummatory phases of sexual behavior, similar to that reported previously in male rats. Those data suggest that the steroid-dependent role of hypothalamic DA in male sexual behavior has been conserved through evolutionary time.

Publication types

  • Comment

MeSH terms

  • Animals
  • Brain / physiology*
  • Dopamine / physiology*
  • Male
  • Sexual Behavior, Animal / physiology*
  • Testosterone / physiology*


  • Testosterone
  • Dopamine