CuS flower-like microspheres with the diameter of about 3-4 microm constructed by nanoflakes with thickness of about 30-40 nm have been successfully synthesized by a simple wet chemical method. In this reaction system, Poly(ethylene glycol) 200 (PEG 200) was used as solvent, CuCl2 2H2O as cuprum source, and thioacetamide (TAA) as sulfur source. The products were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), and high-resolution transmission electron microscopy (HRTEM) in detail. The XRD patterns revealed that the products were pure hexagonal phase of CuS. Experiments with various parameters indicated that the reaction temperature and molar ratio of CuCl2 2H2O to thioacetamide had strong effects on the sizes and morphologies of CuS crystals. A possible growth mechanism on the formation of CuS microspheres was proposed. The PEG 200 acted as solvent, complexing agent, and soft template in this synthesis. Furthermore, optical studies of the products including UV-Vis absorption spectrum and photoluminescence spectrum have also been carried out.