Dopamine agonists in the treatment of prolactinoma: are they still first choice?

Intern Med J. 2011 Feb;41(2):156-61. doi: 10.1111/j.1445-5994.2010.02410.x.

Abstract

Dopamine agonist therapy has been the cornerstone treatment for prolactinoma since the 1970s, replacing surgery in the primary management of this condition. These agents are effective in the management of prolactin excess, have a low side-effect profile, and in some cases may even be curative. However, recent studies of high dose dopamine agonists used in Parkinson's disease have raised the possibility that these drugs may be associated with cardiac valvulopathy. This paper discusses the modern use of dopamine agonists in a patient with prolactinoma.

Publication types

  • Review

MeSH terms

  • Animals
  • Choice Behavior*
  • Dopamine Agonists / therapeutic use*
  • Humans
  • Prolactinoma / drug therapy*
  • Treatment Outcome

Substances

  • Dopamine Agonists