Wound healing: a new approach to the topical wound care

Cutan Ocul Toxicol. 2011 Jun;30(2):92-9. doi: 10.3109/15569527.2010.539586. Epub 2010 Dec 10.


Cutaneous wound healing is a complex and well-coordinated interaction between inflammatory cells and mediators, establishing significant overlap between the phases of wound healing. Wound healing is divided into three major phases: inflammatory phase, proliferative phase, and remodeling phase. Unlike the acute wound, the nonhealing wound is arrested in one of the phases of healing, typically the inflammatory phase. A systematic approach to the management of the chronic nonhealing wound emphasizes three important elements of wound bed preparation in chronic wounds: debridement, moisture, and countering bacterial colonization and infection. In this article, wound-healing process and new approaches to the topical wound care have been reviewed.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Bacterial Infections / drug therapy
  • Bacterial Infections / prevention & control
  • Debridement / methods
  • Humans
  • Wound Healing / physiology*
  • Wounds and Injuries / therapy*


  • Anti-Bacterial Agents