Poor results with percutaneous endoscopic jejunostomy

Gastrointest Endosc. 1990 May-Jun;36(3):257-60. doi: 10.1016/s0016-5107(90)71018-8.


A percutaneous endoscopic gastrostomy was placed in 20 malnourished patients to serve as a conduit for passage of a percutaneous endoscopic jejunostomy (PEJ) catheter for delivery of alimentation directly into the small bowel. Serious complications occurred in 95% of the patients and 50% of the subjects died. Aspiration was the most common adverse event and accounted for all deaths. Ten of 15 subjects (67%) treated with a PEJ to prevent aspiration continued to aspirate after the catheter was placed. PEJ tube failures were documented in 14 subjects (70%) and occurred because of occlusion, leakage, malposition, extrusion, cracking, kinking, or rupture of the catheter. These problems rendered the PEJ nonfunctional 18% of the time. Large manpower and resource investments were required to manage the PEJ and its complications. Our results suggest that enteral feeding through a PEJ does not prevent aspiration. Serious PEJ-related morbidity (95%), mortality (50%), and catheter failures (70%) occur. Refinements in methodology and catheter design will be required before additional use of this technique can be recommended.

MeSH terms

  • Aged
  • Endoscopy
  • Enteral Nutrition / adverse effects*
  • Enteral Nutrition / methods
  • Equipment Failure
  • Gastroesophageal Reflux / etiology
  • Gastrointestinal Hemorrhage / etiology
  • Humans
  • Jejunostomy / adverse effects*
  • Jejunostomy / instrumentation
  • Jejunostomy / methods
  • Male
  • Nutrition Disorders / therapy*
  • Pneumonia, Aspiration / etiology*
  • Retrospective Studies