Chronic kidney disease after hematopoietic stem cell transplantation

Semin Nephrol. 2010 Nov;30(6):627-34. doi: 10.1016/j.semnephrol.2010.09.010.

Abstract

Acute and chronic kidney diseases occur after hematopoietic stem cell transplantation. These are caused by the transplant itself, and the complications of transplant. Recent estimates show that near 15% of subjects undergoing hematopoietic stem cell transplantation will develop chronic kidney disease, which is a complication rate that can affect outcome and reduce survival. Investigation of the causes of chronic kidney disease is needed, as are ways to prevent, mitigate, and treat it.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Animals
  • Hematopoietic Stem Cell Transplantation / adverse effects*
  • Humans
  • Kidney Diseases / complications
  • Kidney Transplantation
  • Renal Insufficiency, Chronic / diagnosis
  • Renal Insufficiency, Chronic / epidemiology
  • Renal Insufficiency, Chronic / etiology*
  • Renal Insufficiency, Chronic / therapy
  • Whole-Body Irradiation / adverse effects*