Oculomotor nerve paralysis induced by alpha II-interferon

Acta Neurol Belg. 1990;90(2):111-4.


We present a case of bilateral oculomotor nerve paralysis induced by alpha II-interferon in a patient with hairy-cell leukemia. After the drug was withdrawn, the neurological abnormalities disappeared. The more frequent neurological psychiatric, and electroencephalographic side effects are reviewed.

Publication types

  • Case Reports

MeSH terms

  • Humans
  • Interferon Type I / adverse effects*
  • Interferon alpha-2
  • Interferon-alpha / adverse effects*
  • Interferon-alpha / therapeutic use
  • Leukemia, Hairy Cell / therapy
  • Male
  • Middle Aged
  • Ophthalmoplegia / chemically induced*
  • Recombinant Proteins


  • Interferon Type I
  • Interferon alpha-2
  • Interferon-alpha
  • Recombinant Proteins