The role of imaging and molecular imaging in the early detection of metabolic and cardiovascular dysfunctions

Int J Obes (Lond). 2010 Dec:34 Suppl 2:S67-81. doi: 10.1038/ijo.2010.242.


Despite intense effort, obesity is still rising throughout the world. Links between obesity and cardiovascular diseases are now well established. Most of the cardiovascular changes related to obesity can be followed by magnetic resonance imaging (MRI) or by magnetic resonance spectroscopy (MRS). In particular, we will see in this review that MRI/MRS is extremely well suited to depict (1) changes in cardiac mass and function, (2) changes in stroke volume, (3) accumulation of fat inside the mediastinum or even inside the cardiomyocytes, (4) cell viability and (5) molecular changes during early cardiovascular diseases.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Cardiovascular Diseases / diagnosis*
  • Cardiovascular Diseases / physiopathology
  • Early Diagnosis
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Magnetic Resonance Spectroscopy
  • Male
  • Metabolic Syndrome / diagnosis*
  • Metabolic Syndrome / physiopathology
  • Obesity / complications*
  • Obesity / physiopathology