The tale of protein lysine acetylation in the cytoplasm

J Biomed Biotechnol. 2011;2011:970382. doi: 10.1155/2011/970382. Epub 2010 Nov 28.

Abstract

Reversible posttranslational modification of internal lysines in many cellular or viral proteins is now emerging as part of critical signalling processes controlling a variety of cellular functions beyond chromatin and transcription. This paper aims at demonstrating the role of lysine acetylation in the cytoplasm driving and coordinating key events such as cytoskeleton dynamics, intracellular trafficking, vesicle fusion, metabolism, and stress response.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Acetylation
  • Animals
  • Cytoplasm / metabolism*
  • Humans
  • Lysine / metabolism*
  • Protein Processing, Post-Translational*
  • Proteins / metabolism*
  • Signal Transduction

Substances

  • Proteins
  • Lysine