Abstract
We have synthesized an intrinsically fluorescent recognition ligand that combines the high fluorescence quantum yield (>50%) of oligonucleotide templated AgNCs with the specificity and strong binding affinity of DNA aptamers for their target proteins, to develop a new strategy for detection of specific proteins.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Aptamers, Nucleotide / chemistry*
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Humans
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Ligands
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Nanostructures / chemistry*
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Oligonucleotides / chemistry
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Quantum Theory
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Silver / chemistry*
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Spectrometry, Fluorescence / methods*
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Thrombin / analysis*
Substances
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Aptamers, Nucleotide
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Ligands
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Oligonucleotides
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Silver
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Thrombin