Synthesis of DNA-interactive pyrrolo[2,1-c][1,4]benzodiazepines (PBDs)

Chem Rev. 2011 Apr 13;111(4):2815-64. doi: 10.1021/cr100120f. Epub 2010 Dec 17.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Benzodiazepines / chemical synthesis*
  • Benzodiazepines / chemistry
  • Benzodiazepines / pharmacology
  • DNA / metabolism
  • Humans
  • Models, Molecular
  • Pyrroles / chemical synthesis*
  • Pyrroles / chemistry
  • Pyrroles / pharmacology

Substances

  • Pyrroles
  • pyrrolo(2,1-c)(1,4)benzodiazepine
  • Benzodiazepines
  • DNA