A novel enzymatic rearrangement

Chem Biol. 2010 Dec 22;17(12):1269-70. doi: 10.1016/j.chembiol.2010.12.003.


Human Fe(II)-α-ketoglutarate-dependent dioxygenases are a diverse enzyme family involved in a number of biological processes, from collagen biosynthesis to transcription. In this issue, Leung et al. (2010) add a new reaction to their ever-expanding catalytic repertoire.

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