Monomer elution from nanohybrid and ormocer-based composites cured with different light sources

Dent Mater. 2011 Apr;27(4):371-8. doi: 10.1016/j.dental.2010.11.017. Epub 2010 Dec 18.

Abstract

Objectives: To study monomer elution from four resin-based composites (RBCs) cured with different light sources.

Methods: Twenty-eight premolars were randomly allocated to four groups. Standardized cavities were prepared and restored with a nanohybrid (Filtek Supreme XT or Tetric EvoCeram), an ormocer (Admira) or a microhybrid RBC (Filtek Z250) which served as control. Buccal restorations were cured with a halogen and oral restorations with an LED light-curing unit. Elution of diurethane dimethacrylate (UDMA), Bisphenol A diglycidylether methacrylate (BisGMA), triethylene glycol dimethacrylate (TEGDMA) and 2-hydroxyethyl methacrylate (HEMA) was analyzed using high-performance liquid chromatography (HPLC) 1h to 28 days post-immersion in 75% ethanol. Data were analyzed using multivariate and repeated measures analysis of variance (α = 0.05).

Results: The greatest elution of UDMA and BisGMA occurred from Tetric EvoCeram and the least from Filtek Z250 (p < 0.05). LED and halogen light-curing units gave similar results for all RBCs (p > 0.05) except Tetric EvoCeram which showed greater elution for the LED unit (p < 0.05). TEGDMA was below the limit of quantification. HEMA eluted in similar concentrations from Filtek Supreme and Tetric EvoCeram (p > 0.05).

Significance: The two nanohybrid RBCs eluted more cross-linking monomers than the ormocer and the control microhybrid RBC. Continuous elution over 28 days indicates that RBCs act as a chronic source of monomers in clinical conditions. Light source may affect monomer elution since differences were found for one out of four RBCs. Mathematical models for elution kinetics of UDMA and BisGMA indicated two elution mechanisms.

Publication types

  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bicuspid
  • Bisphenol A-Glycidyl Methacrylate / analysis
  • Bisphenol A-Glycidyl Methacrylate / chemistry
  • Ceramics / chemistry*
  • Ceramics / radiation effects
  • Chromatography, High Pressure Liquid
  • Composite Resins / chemistry*
  • Composite Resins / radiation effects
  • Cross-Linking Reagents / analysis
  • Cross-Linking Reagents / chemistry
  • Curing Lights, Dental / classification*
  • Dental Cavity Preparation / methods
  • Dental Materials / chemistry*
  • Dental Materials / radiation effects
  • Dental Restoration, Permanent
  • Ethanol / chemistry
  • Humans
  • Methacrylates / analysis
  • Methacrylates / chemistry
  • Methacrylates / radiation effects
  • Nanocomposites / chemistry*
  • Nanocomposites / radiation effects
  • Organically Modified Ceramics
  • Polyethylene Glycols / analysis
  • Polyethylene Glycols / chemistry
  • Polymethacrylic Acids / analysis
  • Polymethacrylic Acids / chemistry
  • Polyurethanes / analysis
  • Polyurethanes / chemistry
  • Silanes / chemistry*
  • Silanes / radiation effects
  • Siloxanes / chemistry
  • Siloxanes / radiation effects
  • Solvents / chemistry
  • Time Factors

Substances

  • Composite Resins
  • Cross-Linking Reagents
  • Dental Materials
  • Filtek Supreme Plus
  • Filtek Z250
  • Methacrylates
  • Organically Modified Ceramics
  • Polymethacrylic Acids
  • Polyurethanes
  • Silanes
  • Siloxanes
  • Solvents
  • Tetric EvoCeram
  • admira
  • urethane dimethacrylate luting resin
  • triethylene glycol dimethacrylate
  • Ethanol
  • Polyethylene Glycols
  • Bisphenol A-Glycidyl Methacrylate
  • hydroxyethyl methacrylate