[Clearance effect of 3H-cholesterol by Apo-AI/DPPC liposome from cultured SMC of rabbits and tree shrew]

Zhonghua Bing Li Xue Za Zhi. 1990 Mar;19(1):12-5.
[Article in Chinese]

Abstract

Micellar liposomes were prepared by using Apo-AI from rabbit or tree shrew and dipalmitoylphosphatidyl choline (DPPC), with or without cholesterol through a rapid dialysis method. An obvious ability was noticed in clearing of 3H-cholesterol from the cultured smooth muscle cells (SMC) and a cross effect of Apo-AI originated from either rabbit's or tree shrew's serum on the clearance rate of 3H-cholesterol from the cultured SMC of these two species of animals was also obtained.

Publication types

  • English Abstract

MeSH terms

  • 1,2-Dipalmitoylphosphatidylcholine / pharmacology*
  • Animals
  • Aorta
  • Apolipoprotein A-I
  • Apolipoproteins A / pharmacology*
  • Cells, Cultured
  • Cholesterol / metabolism*
  • Lipoproteins, HDL / pharmacology*
  • Liposomes
  • Metabolic Clearance Rate / drug effects
  • Muscle, Smooth, Vascular / cytology*
  • Rabbits
  • Tupaiidae

Substances

  • Apolipoprotein A-I
  • Apolipoproteins A
  • Lipoproteins, HDL
  • Liposomes
  • 1,2-Dipalmitoylphosphatidylcholine
  • Cholesterol