Pulmonary Crohn's disease: A rare extra-intestinal manifestation treated with infliximab

J Crohns Colitis. 2009 Sep;3(3):207-11. doi: 10.1016/j.crohns.2009.03.007. Epub 2009 May 6.


Crohn's disease is a chronic inflammatory bowel disease often presenting with extra-intestinal manifestations. However, pulmonary involvement is quite rare. We report a case of Crohn's disease with pulmonary extra-intestinal manifestation (bronchiolitis obliterans organizing pneumonia-like changes) treated with infliximab. Furthermore, we present an overview of cases of inflammatory bowel disease with lung involvement, treated with tumor necrosis factor-α antagonists. In this case, when infliximab was given, a significant resolution of the pulmonary changes was achieved.