A systematic review of the effectiveness of oral health promotion activities among patients with cardiovascular disease

Int J Cardiol. 2011 Sep 15;151(3):261-7. doi: 10.1016/j.ijcard.2010.11.014. Epub 2010 Dec 21.


Aims: This study aimed to review the effectiveness of oral health promotion activities conducted among patients with cardiovascular disease.

Methods and results: Three electronic databases were searched for effective papers using standardized search methods, and key findings of effective studies were summarized. The initial search yielded 3101 papers but only 8 studies met the criteria for this review: 3 were randomized controlled studies, 3 were pre-/post group interventions, 1 was a randomized split-mouth study, and 1 was a quasi-experimental study. Studies retrieved concerned oral health promotion activities in patients with coronary heart disease, hypertension, heart transplantation, and stroke. Interventions comprised periodontal treatment performed by dental personnel, and oral hygiene interventions provided by nursing home care assistants. Outcomes included improvements in periodontal health, and modifications of systemic inflammatory markers. No studies, however, evaluated the effects of oral health promotion interventions on oral microflora.

Conclusion: There are limited studies on the efficacy of oral health promotion activities in patients with cardiovascular disease, particularly stroke patients. Oral health promotion activities appear to produce improvements in periodontal health, and also result in changes to systemic markers of inflammation and endothelial function (at least) in the short term. Whether these effects can ultimately lower the risk of secondary cardiovascular events has not yet been determined.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Cardiovascular Diseases / epidemiology
  • Cardiovascular Diseases / prevention & control*
  • Clinical Trials as Topic / methods
  • Health Promotion / methods
  • Health Promotion / standards*
  • Humans
  • Oral Health / education
  • Oral Health / standards*
  • Oral Hygiene / methods
  • Oral Hygiene / standards*
  • Patient Education as Topic / methods
  • Patient Education as Topic / standards
  • Treatment Outcome