Response of arteriovenous malformations to gamma knife therapy evaluated with pulsed arterial spin-labeling MRI perfusion

AJR Am J Roentgenol. 2011 Jan;196(1):15-22. doi: 10.2214/AJR.10.5290.


Objective: The goal of this study was to use pulsed arterial spin-labeling (PASL) MRI to evaluate the effect of gamma knife treatment on arteriovenous malformation (AVM) blood flow by measuring perfusion of the AVM nidus and nearby vascular territories.

Conclusion: PASL can show and quantify the steal phenomena and the relative flow rates within the AVM nidus and may be used to follow AVM perfusion over time to assess treatment efficacy.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Analysis of Variance
  • Blood Flow Velocity
  • Cerebrovascular Circulation
  • Child
  • Female
  • Humans
  • Intracranial Arteriovenous Malformations / pathology
  • Intracranial Arteriovenous Malformations / surgery*
  • Magnetic Resonance Angiography / methods*
  • Male
  • Middle Aged
  • Radiosurgery / instrumentation*
  • Retrospective Studies
  • Spin Labels*


  • Spin Labels