Thermal hypesthesia in patients with complex regional pain syndrome related dystonia

J Neural Transm (Vienna). 2011 Apr;118(4):599-603. doi: 10.1007/s00702-010-0558-5. Epub 2010 Dec 29.


The quantitative thermal test showed cold and warmth hypesthesia without increased heat pain sensitivity in the affected limbs of complex regional pain syndrome (CRPS) patients with tonic dystonia (n = 44) in comparison with healthy controls with a similar age and sex distribution (n = 35). The degrees of cold and warmth hypesthesia were strongly correlated. We conclude that dysfunction in small nerve fiber (i.e., C and Aδ) processing is present in patients with CRPS-related dystonia.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Complex Regional Pain Syndromes / complications
  • Complex Regional Pain Syndromes / physiopathology*
  • Dystonic Disorders / etiology
  • Dystonic Disorders / physiopathology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Nerve Fibers, Unmyelinated / physiology
  • Somatosensory Disorders / diagnosis*
  • Somatosensory Disorders / etiology
  • Somatosensory Disorders / physiopathology*
  • Thermosensing / physiology*
  • Young Adult