MR imaging of optic nerve lesions: value of gadopentetate dimeglumine and fat-suppression technique

AJR Am J Roentgenol. 1990 Oct;155(4):849-54. doi: 10.2214/ajr.155.4.2119121.


Eleven patients with known or suspected optic nerve lesions and eight normal subjects were examined with spin-echo technique at 1.5 T with unenhanced T1-weighted imaging, IV gadopentetate-dimeglumine-enhanced T1-weighted imaging, and enhanced T1-weighted imaging with fat suppression. Two pathologically proved and four presumed optic nerve meningiomas demonstrated significant enhancement and were best seen with the fat-suppression technique. None of the three presumed optic nerve gliomas nor the optic nerves of normal subjects demonstrated qualitative enhancement. We conclude that the use of a fat-suppression technique with gadopentetate dimeglumine enhancement improves delineation of enhancing optic nerve lesions. This technique should be useful for evaluating other anatomic regions where enhancing tissue marginates fat.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adipose Tissue / pathology
  • Adult
  • Aged
  • Cranial Nerve Neoplasms / diagnosis*
  • Gadolinium DTPA
  • Glioma / diagnosis
  • Humans
  • Image Enhancement / methods*
  • Magnetic Resonance Imaging*
  • Meningioma / diagnosis
  • Middle Aged
  • Optic Nerve Diseases / diagnosis*
  • Organometallic Compounds*
  • Pentetic Acid*


  • Organometallic Compounds
  • Pentetic Acid
  • Gadolinium DTPA