Biomolecular studies by circular dichroism

Front Biosci (Landmark Ed). 2011 Jan 1;16:61-73. doi: 10.2741/3676.


In this review, we shall outline the basic principles of circular dichroism (CD) indicating the types of structural information relevant to the study of biomolecules, such as proteins or DNA. We are mainly interested to show the utility of this technique to study protein-ligand, DNA-ligand and protein-DNA interactions.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Circular Dichroism / methods*
  • DNA / chemistry*
  • Ligands
  • Protein Binding
  • Protein Kinase Inhibitors / chemistry
  • Protein Structure, Secondary
  • Proteins / chemistry*


  • Ligands
  • Protein Kinase Inhibitors
  • Proteins
  • DNA