Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010 Dec 15;2011:219578.
doi: 10.4061/2011/219578.

Fish Consumption Moderates Depressive Symptomatology in Elderly Men and Women From the IKARIA Study

Free PMC article

Fish Consumption Moderates Depressive Symptomatology in Elderly Men and Women From the IKARIA Study

Christina Chrysohoou et al. Cardiol Res Pract. .
Free PMC article


Background. The aim was to examine the association of depressive symptoms with fish eating habits, in elderly individuals. Methods. From June to October of 2009, we studied 330 men and 343 women, aged 65 to 100 years, permanent inhabitants of Ikaria Island. Among several characteristics, depression was assessed with the Geriatric Depression scale (GDS range 0-15), while dietary habits through a valid semiquantitative food frequency questionnaire. Results. Women had significantly higher values of the GDS compared to men (4.8 ± 3.5 versus 3.3 ± 3.1, P = .001). Participants in the upper tertile of depression scale ate less frequent fish and consumed higher quantities of alcohol, compared to those in the lowest tertile (all P < .05). Regarding fish consumption, 50% of the individuals reported consuming 1-2 times weekly, 32% 3 to 5 times weekly, 11% 2-3 times monthly, while the rest reported rare (4.5%) and everyday (1.2%) consumption. Logistic regression showed that increased fish consumption (>3 times/week versus never/rare) was inversely associated with the odds of having GDS greater the median value (i.e., 4) (odds ratio = 0.34, 95% CI: 0.19, 0.61), after controlling for several cofounders. Conclusion. Frequent fish consumption in elderly seems to moderate depression mood.

Similar articles

See all similar articles

Cited by 4 articles


    1. World Health Organization. The World Health Report 2002. Geneva, Switzerland: WHO; 2001. Reducing risks, promoting healthy life.
    1. Panagiotakos DB, Kinlaw M, Papaerakleous N, Papoutsou S, Toutouzas P, Polychronopoulos E. Depressive symptomatology and the prevalence of cardiovascular risk factors among older men and women from Cyprus; The MEDIS (Mediterranean Islands Elderly) epidemiological study. Journal of Clinical Nursing. 2008;17(5):688–695. - PubMed
    1. Murray CJL, Lopez AD. Alternative projections of mortality and disability by cause 1990–2020: Global Burden of Disease Study. The Lancet. 1997;349(9064):1498–1504. - PubMed
    1. Keys A, Menotti A, Karvonen MJ. The diet and 15-year death rate in the seven countries study. American Journal of Epidemiology. 1986;124(6):903–915. - PubMed
    1. Chrysohoou C, Panagiotakos DB, Pitsavos C, Das UN, Stefanadis C. Adherence to the Mediterranean diet attenuates inflammation and coagulation process in healthy adults: the ATTICA study. Journal of the American College of Cardiology. 2004;44(1):152–158. - PubMed