Retinal thickness in myopic and non-myopic eyes

Ophthalmic Physiol Opt. 2010 Nov;30(6):776-84. doi: 10.1111/j.1475-1313.2010.00788.x.


Purpose: To investigate the retinal thickness profile in myopic and non-myopic eyes.

Methods: The retinal thickness profile of 30 myopic eyes [spherical equivalent error (SER) between -6.00 and -13.63 D] and 31 non-myopic eyes (SER between +2.75 and -0.50 D) were measured using the Stratus OCT (Carl Zeiss Meditec, Dublin, CA, USA). Two scan types were used: the Macular Thickness Map and the Customized Line Scan for a central 80° horizontal retinal thickness profile.

Results: At foveal center and fovea, myopic eyes had a thicker retina than the non-myopic group (p = 0.002 and 0.044, respectively). At other zones of the macula, the retina was significantly thinner in myopic eyes compared to non-myopic eyes (p < 0.01, unpaired t-test). From 40° nasal to 40° temporal retina, a general reduction of retinal thickness was observed across the myopic retina compared to the non-myopic retina except at 20° nasal to fixation.

Conclusions: There was general reduction in retinal thickness within the horizontal central 80° in myopic eyes compared with non-myopic eyes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Case-Control Studies
  • Eye / pathology
  • Female
  • Humans
  • Macula Lutea / pathology
  • Male
  • Myopia / pathology*
  • Retina / pathology*
  • Tomography, Optical Coherence / methods
  • Young Adult