In vivo imaging of the human rod photoreceptor mosaic

Opt Lett. 2011 Jan 1;36(1):31-3. doi: 10.1364/OL.36.000031.


Although single cone receptors have been imaged <i>in vivo</i>, to our knowledge there has been no observation of rods in the living normal eye. Using an adaptive optics ophthalmoscope and post processing, evidence of a rod mosaic was observed at 5° and 10° eccentricities in the horizontal temporal retina. For four normal human subjects, small structures were observed between the larger cones and were observed repeatedly at the same locations on different days, and with varying wavelengths. Image analysis gave spacings that agree well with rod measurements from histological data.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adult
  • Humans
  • Image Processing, Computer-Assisted
  • Molecular Imaging / methods*
  • Retinal Rod Photoreceptor Cells / cytology*
  • Young Adult