Progressive airflow limitation is a feature of children with severe asthma

J Allergy Clin Immunol. 2011 Jan;127(1):282-4. doi: 10.1016/j.jaci.2010.10.036.


Children with severe asthma have a premature loss of lung function during the adolescent years that is associated with increased symptom frequency and greater allergic sensitization during childhood.

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Anti-Asthmatic Agents / therapeutic use
  • Asthma / drug therapy
  • Asthma / physiopathology*
  • Child
  • Female
  • Forced Expiratory Volume
  • Humans
  • Male
  • Respiratory Function Tests


  • Adrenal Cortex Hormones
  • Anti-Asthmatic Agents