The neural circuitry of autism

Neurotox Res. 2011 Oct;20(3):201-14. doi: 10.1007/s12640-010-9234-7. Epub 2011 Jan 7.

Abstract

Autism is a complex neurodevelopmental disorder, characterized by deficits in social emotional, and language domains, as well as repetitive restrictive behaviors. The vast heterogeneity of the clinical and behavioral symptoms has made it rather difficult to delineate the neural circuitry affiliated with these domains of dysfunction. The current review aims at broadly outlining the latest research into the neurobiology and neural circuitry underlying the core domains of deficits in autism. We further discuss new avenues of research that can further our understanding of the dimensions of this complex disorder.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Autistic Disorder / complications
  • Autistic Disorder / pathology*
  • Brain / pathology
  • Brain / physiopathology*
  • Cognition Disorders / etiology
  • Cognition Disorders / pathology
  • Diagnostic Imaging
  • Electroencephalography / methods
  • Evoked Potentials / physiology
  • Executive Function
  • Humans
  • Neural Pathways / physiopathology
  • Neuropsychological Tests
  • Social Behavior