[A nested case-control study on the influencing factors of tuberculosis among people living with HIV/AIDS in Hunan province]

Zhonghua Liu Xing Bing Xue Za Zhi. 2010 Feb;31(2):151-4.
[Article in Chinese]

Abstract

Objective: To determine the risk factors related to tuberculosis infection among people living with HIV/AIDS and to develop strategies for preventing the co-infection.

Methods: A 1:2 matched nested case-control study was carried out to analyze the influencing factors of tuberculosis among people living with HIV/AIDS.

Results: 1018 people living with HIV/AIDS were followed up for one year with a total number of 736.75 person-years, among them 62 tuberculosis cases were diagnosed. The incidence density of tuberculosis among people living with HIV/AIDS was 8.42 persons per 100 person-years. Factors as education level(OR = 0.483), vaccination history of Bacille Calmette Guerin (OR = 0.561), CD(4)(+) count T-lymphocyte (OR = 0.356), unemployment (OR = 1.976), living alone (OR = 2.646), and smoking (OR = 2.215) were significantly related to the prevalence of tuberculosis among people living with HIV/AIDS.

Conclusion: High education level, with vaccination history of Bacille Calmette Guerin and high level of CD(4)(+) T-lymphocyte count were protective factors while being unemployed, living alone, and smoking habit were risk factors related to the prevalence of tuberculosis among people living with HIV/AIDS.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • AIDS-Related Opportunistic Infections / epidemiology*
  • Acquired Immunodeficiency Syndrome / complications*
  • Acquired Immunodeficiency Syndrome / epidemiology
  • Adult
  • Case-Control Studies
  • China / epidemiology
  • Coinfection
  • Female
  • HIV Infections / complications*
  • HIV Infections / epidemiology
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Risk Factors
  • Tuberculosis / epidemiology*