Effects of mental workload on long-latency auditory-evoked-potential, salivary cortisol, and immunoglobulin A

Neurosci Lett. 2011 Mar 10;491(1):31-4. doi: 10.1016/j.neulet.2011.01.002. Epub 2011 Jan 5.

Abstract

This paper researches on the effects of mental workload on long-latency auditory-evoked-potential (AEP), salivary cortisol, and immunoglobulin A (IgA). 20 Healthy subjects (11 males and 9 females) participated in the experiment voluntarily. The mental task consisted of two parts: arithmetic task and reading comprehension task. The Latencies of N1, P2, N2, P3, and mismatch negativity (MMN) all increased significantly after the mental tasks were adopted at all of the three recording sites: Cz, Fz, and Pz (p<0.05). In this experiment, changes of salivary cortisol and s-IgA levels due to mental tasks were not significant. With the introduction of mental tasks, more processing resources are allocated to the primary task (mental task), and decreased processing resources available for the secondary task (auditory task), which is reflected on the increases in the latencies of probe-evoked AEP components.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cognition / physiology*
  • Evoked Potentials, Auditory / physiology*
  • Female
  • Humans
  • Hydrocortisone / metabolism*
  • Immunoglobulin A / metabolism*
  • Male
  • Mental Processes / physiology*
  • Problem Solving / physiology*
  • Reaction Time / physiology*
  • Young Adult

Substances

  • Immunoglobulin A
  • Hydrocortisone