Neurosurgical considerations in von Hippel-Lindau disease

M M Beitner; I Winship; K J Drummond

doi:10.1016/j.jocn.2010.04.054

Neurosurgical considerations in von Hippel-Lindau disease

J Clin Neurosci. 2011 Feb;18(2):171-80. doi: 10.1016/j.jocn.2010.04.054. Epub 2011 Jan 6.

Authors

M M Beitner¹, I Winship, K J Drummond

Affiliation

¹ Department of Neurosurgery, Royal Melbourne Hospital, Grattan Street, Parkville, Victoria 3050, Australia. Melissa.Beitner@mh.org.au

PMID: 21215639
DOI: 10.1016/j.jocn.2010.04.054

Abstract

Von Hippel-Lindau disease is an inherited syndrome predisposing to a variety of benign and malignant neoplasms of the central nervous system and viscera that requires comprehensive screening and follow-up of individuals and their families. As such, it is important for the neurosurgeon to be aware of its clinical features and management issues. In this article we review the clinical aspects, management and surveillance of von Hippel-Lindau disease for neurosurgical practice.

Publication types

Review

MeSH terms

Central Nervous System Neoplasms / diagnosis*
Central Nervous System Neoplasms / physiopathology
Central Nervous System Neoplasms / surgery*
Hemangioblastoma / diagnosis
Hemangioblastoma / physiopathology
Hemangioblastoma / surgery
Humans
Neoplasm Recurrence, Local / prevention & control
Neurosurgical Procedures / adverse effects
Neurosurgical Procedures / methods
Neurosurgical Procedures / standards*
Postoperative Complications / etiology
Postoperative Complications / physiopathology
Postoperative Complications / prevention & control
von Hippel-Lindau Disease / diagnosis*
von Hippel-Lindau Disease / physiopathology
von Hippel-Lindau Disease / surgery*