KPC-2 carbapenemase-producing Klebsiella pneumoniae isolates from patients with Cystic Fibrosis

J Cyst Fibros. 2011 Mar;10(2):140-2. doi: 10.1016/j.jcf.2010.12.003. Epub 2011 Jan 8.


Bacteria producing Klebsiella pneumoniae carbapenemases (KPCs) are rapidly emerging as a cause of multidrug-resistant infections worldwide. KPCs enzyme are plasmid-borne and can accumulate and transfer resistance determinants to other classes of antibiotics.We report two cases of KPC-2 carbapenemase-producing Klebsiella pneumoniae isolates from Cystic Fibrosis patients.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Bacterial Proteins / metabolism*
  • Cystic Fibrosis / microbiology*
  • Female
  • Humans
  • Klebsiella Infections / microbiology*
  • Klebsiella pneumoniae / enzymology*
  • Klebsiella pneumoniae / isolation & purification
  • Young Adult
  • beta-Lactamases / metabolism*


  • Bacterial Proteins
  • beta-Lactamases
  • beta-lactamase KPC-2, Klebsiella pneumoniae
  • carbapenemase-2, Klebsiella pneumoniae