Large congenital melanocytic nevus with metastatic melanoma with a probable primary in the lung

Indian J Dermatol Venereol Leprol. 2011 Jan-Feb;77(1):51-4. doi: 10.4103/0378-6323.74980.

Abstract

Large congenital melanocytic nevi (> 20 cm in greatest diameter) are very rare and are seen in approximately 1 in 20,000 newborns. The major risk these patients face is the development of neurocutaneous melanosis or malignant melanoma. We report a rare case of large congenital melanocytic nevus with metastatic melanoma in a 40-year-old woman. In this case, though the primary was not established with certainty, on the basis of clinical course and radiological evaluation of various organs, we presume that the primary could be in the lung.

Publication types

  • Case Reports

MeSH terms

  • Biopsy, Needle
  • Brain Neoplasms / pathology
  • Brain Neoplasms / secondary*
  • Brain Neoplasms / therapy
  • Combined Modality Therapy
  • Disease Progression
  • Fatal Outcome
  • Female
  • Humans
  • Immunohistochemistry
  • Lung Neoplasms / diagnostic imaging
  • Lung Neoplasms / pathology*
  • Lung Neoplasms / therapy
  • Melanoma / diagnosis
  • Melanoma / secondary*
  • Melanoma / therapy
  • Middle Aged
  • Neoplasms, Multiple Primary / diagnostic imaging
  • Neoplasms, Multiple Primary / pathology*
  • Neoplasms, Multiple Primary / therapy
  • Nevus, Pigmented / congenital*
  • Nevus, Pigmented / pathology
  • Nevus, Pigmented / therapy
  • Radiography, Thoracic
  • Skin Neoplasms / congenital*
  • Skin Neoplasms / pathology
  • Skin Neoplasms / therapy
  • Tomography, X-Ray Computed / methods