In vitro comparison of mechanical and degradation properties of equivalent absorbable suture materials from two different manufacturers

Vet Surg. 2011 Feb;40(2):223-7. doi: 10.1111/j.1532-950X.2010.00768.x. Epub 2011 Jan 11.

Abstract

Objective: To compare the mechanical, knotting, and absorption properties of 3 synthetic absorbable suture materials (polyglactin 910, polydioxanone, poliglecaprone 25) from 2 different manufacturers (Huaiyin Medical Instruments Co. Ltd. and Ethicon Inc.).

Sample population: Suture material samples from the same manufacturing lot for each suture type and manufacturer.

Methods: Part 1: 10 samples of each suture were incubated in bovine serum and tested for ultimate load and stiffness at days 0, 1, 7, 14, 21, and 28. Part 2: 10 knotted samples were similarly evaluated, without incubation.

Results: Huaiyin polydioxanone had a greater (P<.001) ultimate load on days 0, 1, and 7; and a consistently greater stiffness for the duration of the study, compared with the Ethicon polydioxanone. Ethicon poliglecaprone 25 had a greater ultimate load on days 0, 1, 7 (P<.001); on day 21 Huaiyin had a greater ultimate load. Ethicon poliglecaprone had greater stiffness on days 0, 1, 7 (P<.001). Ethicon polyglactin 910 had a greater (P<.001) ultimate load at all times and a greater stiffness (P<.001) at days 0, 1, 7, and 14 compared with Huaiyin polyglactin 910. Huaiyin polydioxanone and polyglactin 910 had greater knot breaking strengths than Ethicon equivalents (P<.001).

Conclusion: Differences in mechanical properties exist between nominally identical suture materials from different manufacturers.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Dioxanes / chemistry
  • Materials Testing*
  • Polydioxanone / chemistry
  • Polyesters / chemistry
  • Polyglactin 910 / chemistry
  • Sutures*
  • Tensile Strength
  • Time Factors

Substances

  • Dioxanes
  • Polyesters
  • Polydioxanone
  • Polyglactin 910
  • glycolide E-caprolactone copolymer