Predictors of anxiety and depression among people attending diabetes screening: a prospective cohort study embedded in the ADDITION (Cambridge) randomized control trial

Br J Health Psychol. 2011 Feb;16(Pt 1):213-26. doi: 10.1348/135910710X495366.


Objective: This study aimed to identify factors predicting anxiety and depression among people who attend primary care-based diabetes screening.

Design: A prospective cohort study embedded in the ADDITION (Cambridge) randomized control trial.

Methods: Participants (N= 3,240) at risk of diabetes were identified from 10 primary care practices and invited to a stepwise screening programme as part of the ADDITION (Cambridge) trial. Main outcome measures were anxiety and depression at 12 months post-screening assessed using the Hospital Anxiety and Depression Scale (HADS).

Results: Hierarchical linear regressions showed that demographic, clinical, and psychological variables collectively accounted for 52% of the variance in HADS anxiety scores and 53% of the variance in HADS depression scores 12 months after diabetes screening. Screening outcome (positive or negative for diabetes) was not related to differences in anxiety or depression at 12 months. Higher number of self-reported (diabetes) symptoms after first attendance was associated with higher anxiety and depression at 12-month follow-up, after controlling for anxiety and depression after first attendance.

Conclusion: Participants in a diabetes screening programme showed low scores on anxiety and depression scales after first appointment and 1 year later. Diagnosis of diabetes was shown to have a limited psychological impact and may be less important than symptom perception in determining emotional outcomes after participation in diabetes screening.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Anxiety Disorders / epidemiology*
  • Anxiety Disorders / psychology
  • Attitude to Health
  • Cohort Studies
  • Comorbidity
  • Depressive Disorder / epidemiology*
  • Depressive Disorder / psychology
  • Diabetes Mellitus, Type 2 / diagnosis*
  • Diabetes Mellitus, Type 2 / epidemiology
  • Diabetes Mellitus, Type 2 / psychology*
  • Female
  • Follow-Up Studies
  • Health Behavior
  • Humans
  • Male
  • Mass Screening / methods
  • Mass Screening / psychology*
  • Mass Screening / statistics & numerical data
  • Middle Aged
  • Predictive Value of Tests
  • Prospective Studies
  • United Kingdom / epidemiology