Updated recommendations for use of tetanus toxoid, reduced diphtheria toxoid and acellular pertussis (Tdap) vaccine from the Advisory Committee on Immunization Practices, 2010

MMWR Morb Mortal Wkly Rep. 2011 Jan 14;60(1):13-5.


Despite sustained high coverage for childhood pertussis vaccination, pertussis remains poorly controlled in the United States. A total of 16,858 pertussis cases and 12 infant deaths were reported in 2009. Although 2005 recommendations by the Advisory Committee on Immunization Practices (ACIP) called for vaccination with tetanus toxoid, reduced diphtheria toxoid and acellular pertussis (Tdap) for adolescents and adults to improve immunity against pertussis, Tdap coverage is 56% among adolescents and <6% among adults. In October 2010, ACIP recommended expanded use of Tdap. This report provides the updated recommendations, summarizes the safety and effectiveness data considered by ACIP, and provides guidance for implementing the recommendations.

Publication types

  • Practice Guideline

MeSH terms

  • Adolescent
  • Adult
  • Advisory Committees
  • Aged
  • Child
  • Diphtheria-Tetanus-acellular Pertussis Vaccines / administration & dosage*
  • Diphtheria-Tetanus-acellular Pertussis Vaccines / adverse effects
  • Diphtheria-Tetanus-acellular Pertussis Vaccines / immunology
  • Humans
  • Immunization Schedule*
  • Immunization, Secondary
  • Middle Aged
  • United States / epidemiology
  • Whooping Cough / epidemiology
  • Whooping Cough / prevention & control*
  • Young Adult


  • Diphtheria-Tetanus-acellular Pertussis Vaccines