[Applicability and validity of the Dutch version of the Montreal Cognitive Assessment (moCA-d) in diagnosing MCI]

Tijdschr Gerontol Geriatr. 2010 Dec;41(6):231-40. doi: 10.1007/s12439-010-0218-0.
[Article in Dutch]

Abstract

Objective: The MoCA is a new screening test to detect Mild Cognitive Impairment (MCI). Purpose of this study is validating the Dutch version (MoCA-D).

Method: We administered the MoCA-D to healthy control subjects and to elderly with MCI or dementia from a memory disorder outpatient clinic and a geriatric (outpatient) clinic (n = 30, 32, 37 respectively, age > or = 60). Neuropsychological testing was part of the standard procedure for patients to diagnose MCI. Sensitivity, specificity and predictive values (positive: PPV and negative: NPV) of the MoCA-D were assessed.

Results: A significant effect of group was found on MoCA-D total score (F (2.95) =67.9; p < 0.01). With a cutoff score of < or = 25, sensitivity and specificity to detect MCI in relation to healthy controls were 72% and 73%, respectively. PPV and NPV were 84% and 56%, respectively. With a cut-off score of < or = 20, sensitivity to detect dementia in relation to MCI was 100% for severe dementia and 75% for mild dementia. Specificity for dementia was 81%, PPV 94% and NPV 55%.

Conclusion: The MoCA-D distinguishes between healthy elderly, MCI patients and dementia patients. However, in this study, insufficient sensitivity and poor specificity were found. For the present, applying a broader and flexible screening procedure in order to detect MCI seems a more useful method than the interpretation of one test result in particular.

Publication types

  • Validation Study

MeSH terms

  • Aged
  • Case-Control Studies
  • Cognition Disorders / diagnosis*
  • Cognition Disorders / epidemiology
  • Female
  • Geriatric Assessment*
  • Humans
  • Male
  • Netherlands
  • Predictive Value of Tests
  • Prevalence
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Severity of Illness Index
  • Surveys and Questionnaires / standards*
  • Translations