[Influence of health education on compliance with antituberculous chemoprophylaxis in children: a community trial]

Rev Clin Esp. 1990 Jun;187(2):89-93.
[Article in Spanish]


Antituberculous chemoprophylaxis with isoniazide during a period of one year is very useful although it is not readily accepted. A community trial is designed in order to test if three health education interventions increase patients compliance with such treatment in case of tuberculin positive children who are not ill. The two interventions performed by nurses, one by phone, and the second one by a home visit, resulted in statistically significant difference when compared to the control group. This did not occur, however, with the intervention performed by the doctor in his office. A cost-effectiveness study demonstrates that the most efficient intervention has been the phone call.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial
  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Child
  • Community Health Services
  • Cost-Benefit Analysis
  • Evaluation Studies as Topic
  • Humans
  • Isoniazid / administration & dosage*
  • Patient Compliance*
  • Patient Education as Topic / economics*
  • Patient Education as Topic / methods*
  • Random Allocation
  • Tuberculosis / prevention & control*


  • Isoniazid