Hospital epidemiology and infection control in acute-care settings

Clin Microbiol Rev. 2011 Jan;24(1):141-73. doi: 10.1128/CMR.00027-10.


Health care-associated infections (HAIs) have become more common as medical care has grown more complex and patients have become more complicated. HAIs are associated with significant morbidity, mortality, and cost. Growing rates of HAIs alongside evidence suggesting that active surveillance and infection control practices can prevent HAIs led to the development of hospital epidemiology and infection control programs. The role for infection control programs has grown and continues to grow as rates of antimicrobial resistance rise and HAIs lead to increasing risks to patients and expanding health care costs. In this review, we summarize the history of the development of hospital epidemiology and infection control, common HAIs and the pathogens causing them, and the structure and role of a hospital epidemiology and infection control program.

Publication types

  • Historical Article
  • Review

MeSH terms

  • Cross Infection / epidemiology
  • Cross Infection / mortality
  • Cross Infection / prevention & control*
  • Emergency Service, Hospital*
  • History, 19th Century
  • History, 20th Century
  • History, 21st Century
  • Humans
  • Infection Control / history
  • Infection Control / methods*