A post-labeling strategy based on dye-induced peeling of the aptamer off single-walled carbon nanotubes for electrochemical aptasensing

Yingchun Fu; Ting Wang; Lijuan Bu; Qingji Xie; Penghao Li; Jinhua Chen; Shouzhuo Yao

doi:10.1039/c0cc05188h

A post-labeling strategy based on dye-induced peeling of the aptamer off single-walled carbon nanotubes for electrochemical aptasensing

Chem Commun (Camb). 2011 Mar 7;47(9):2637-9. doi: 10.1039/c0cc05188h. Epub 2011 Jan 13.

Authors

Yingchun Fu¹, Ting Wang, Lijuan Bu, Qingji Xie, Penghao Li, Jinhua Chen, Shouzhuo Yao

Affiliation

¹ Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education of China), College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha, P R China.

PMID: 21234471
DOI: 10.1039/c0cc05188h

Abstract

A simple and efficient post-labeling strategy based on dye-induced peeling of the aptamer molecules off single-walled carbon nanotubes was developed for electrochemical aptasensing of thrombin with a detection limit down to 3 pM.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aptamers, Nucleotide / chemistry*
Biosensing Techniques / methods*
Coloring Agents / chemistry*
Electrochemical Techniques / methods*
Electrodes
Gold / chemistry
Microscopy, Atomic Force
Nanotubes, Carbon / chemistry*
Spectrophotometry, Ultraviolet
Thrombin / analysis

Substances

Aptamers, Nucleotide
Coloring Agents
Nanotubes, Carbon
Gold
Thrombin