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, 70 (1), 124-7

A Simple Head-Mountable LED Device for Chronic Stimulation of Optogenetic Molecules in Freely Moving Mice

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A Simple Head-Mountable LED Device for Chronic Stimulation of Optogenetic Molecules in Freely Moving Mice

Youichi Iwai et al. Neurosci Res.

Abstract

We describe a low-cost, small, remotely triggerable LED device for wireless control of transcranial optical stimulation of cortical neurons, for use in freely moving mice. The device is easily mountable on the head of a mouse with a high-polymer block. Using the Thy1-ChR2-YFP transgenic mice, we demonstrate that the device is capable of remotely triggering muscle twitches upon activation of the primary motor cortex in freely moving conditions.

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