Dexmedetomidine as an adjuvant analgesic for intractable cancer pain

J Palliat Med. 2011 Mar;14(3):371-3. doi: 10.1089/jpm.2010.0235. Epub 2011 Jan 17.


Abstract Dexmedetomidine (Precedex®) is an alpha-2 adrenergic agonist that can produce sedation and analgesia without causing respiratory depression. Its use has been described in patients undergoing mechanical ventilation, sedation for surgical and nonsurgical procedures, and prevention of withdrawal. We describe its use as an adjuvant analgesic in a patient with cancer pain refractory to multiple treatment modalities.

Publication types

  • Case Reports

MeSH terms

  • Analgesics, Non-Narcotic / administration & dosage
  • Analgesics, Non-Narcotic / therapeutic use*
  • Chemotherapy, Adjuvant
  • Dexmedetomidine / administration & dosage
  • Dexmedetomidine / therapeutic use*
  • Female
  • Humans
  • Middle Aged
  • Neoplasms / physiopathology*
  • Pain, Intractable / drug therapy*


  • Analgesics, Non-Narcotic
  • Dexmedetomidine