Comparison of Oculus Pentacam and Stratus optical coherence tomography for measurement of central corneal thickness

Cornea. 2011 Jun;30(6):670-4. doi: 10.1097/ICO.0b013e31820128a4.


Purpose: Measurement of central corneal thickness (CCT) plays an essential role in the diagnosis and treatment of many ocular diseases. In this study, we aimed to compare the CCT measurements obtained using the Scheimpflug system (Pentacam; Oculus, Inc) with a retinal optical coherence tomography device (Stratus OCT; Carl Zeiss Meditec, Inc) to examine healthy corneas.

Methods: CCT measurements of 80 eyes belonging to 40 male patients (mean age: 24.48 ± 6.01 years) were evaluated with the Pentacam and the Stratus OCT. The relationship between the CCT values obtained with these 2 devices was examined with a Pearson correlation analysis, a paired t test, and a Bland-Altman analysis.

Results: The average CCT value obtained with Pentacam was 546.11 ± 34.15 μm and that obtained with Stratus OCT was 567.76 ± 35.02 μm. Although the average difference between the devices was 21.65 ± 8.59 μm (P < 0.0001), the measurements obtained with both devices were significantly correlated (r = 0.969, P < 0.0001). In Bland-Altman analysis, there was a high consistency between measurements obtained with either Pentacam or Stratus OCT devices.

Conclusions: Corneal thickness measurements differ depending on the device used. Corneal thicknesses that have been calculated with Pentacam were lower than the values obtained with Stratus OCT. Both devices used for CCT measurement are easily applied, noninvasive, and effective. However, the devices are not interchangeable. Stratus OCT is not optimal for CCT measurement because of the important limitations of using manual measurements, but it can be used if other measurement devices designed for the purpose are not available.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Anthropometry
  • Biometry / methods
  • Cornea / anatomy & histology*
  • Diagnostic Techniques, Ophthalmological / instrumentation*
  • Humans
  • Male
  • Middle Aged
  • Military Personnel
  • Photography / instrumentation
  • Reference Values
  • Reproducibility of Results
  • Tomography, Optical Coherence / instrumentation
  • Turkey
  • Young Adult