Alcohol consumption and risk of renal cell cancer: the NIH-AARP diet and health study

Br J Cancer. 2011 Feb 1;104(3):537-41. doi: 10.1038/sj.bjc.6606089. Epub 2011 Jan 18.


Background: The effect of moderate to heavy drinking (>15 g per day) on renal cell cancer (RCC) risk is unclear.

Method: The relationship between alcohol consumption and RCC was examined in the NIH-AARP Diet and Health Study (n=49 2187, 1814 cases).

Results: Compared with >0 to <5 g per day of alcohol consumption, the multivariate relative risk (95% confidence intervals) for 15 to <30 and 30 g per day was, 0.75 (0.63-0.90) and 0.71 (0.59-0.85), respectively, in men and 0.67 (0.42-1.07) and 0.43 (0.22-0.84), respectively, in women.

Conclusion: Alcohol consumption was inversely associated with RCC in a dose-response manner. The inverse association may be extended to 30 g per day of alcohol intake.

MeSH terms

  • Alcohol Drinking / epidemiology*
  • Carcinoma, Renal Cell / epidemiology*
  • Diet
  • Female
  • Humans
  • Kidney Neoplasms / epidemiology*
  • Male
  • Prospective Studies
  • Risk Factors
  • Surveys and Questionnaires