Structure, conformation, stereodynamics, and absolute configuration of the atropisomers of fluorenylidene derivatives

J Org Chem. 2011 Mar 4;76(5):1487-90. doi: 10.1021/jo1023427. Epub 2011 Jan 20.

Abstract

The barrier for the interconversion of the conformational atropisomers of an aryl fluorenylidene derivative was determined by variable-temperature NMR technique. In the case of a more hindered compound the two atropisomers were isolated and the structure determined by X-ray diffraction. The absolute configuration was assigned by theoretical interpretation of the Electronic Circular Dichroism spectrum (ECD).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Crystallography, X-Ray
  • Fluorenes / chemistry*
  • Molecular Structure
  • Quantum Theory
  • Stereoisomerism

Substances

  • Fluorenes