Evaluation of mutations in the isocitrate dehydrogenase genes in therapy-related and secondary acute myeloid leukaemia identifies a patient with clonal evolution to IDH2 R172K homozygosity due to uniparental disomy

Br J Haematol. 2011 Mar;152(5):669-72. doi: 10.1111/j.1365-2141.2010.08404.x. Epub 2011 Jan 20.
No abstract available

Publication types

  • Letter

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Humans
  • Isocitrate Dehydrogenase / genetics*
  • Leukemia, Myeloid, Acute / genetics*
  • Male
  • Middle Aged
  • Mutation*
  • Neoplasms, Second Primary / genetics*
  • Uniparental Disomy*
  • Young Adult

Substances

  • Isocitrate Dehydrogenase
  • isocitrate dehydrogenase 2, human