Drug resistance trends in Mycobacterium tuberculosis: Blackburn 1985-89

Tubercle. 1990 Dec;71(4):283-5. doi: 10.1016/0041-3879(90)90042-7.

Abstract

Drug resistance in Mycobacterium tuberculosis fell from 15.2% in 1980-1984 to 6.5% in 1985-89 in the Indian subcontinent (ISC) ethnic group and remained low in the white ethnic group. Resistance to isoniazid, which is of particular clinical significance, fell from 6.1% in 1980-84 to 2.7% in 1985-1989 in the ISC group. Factors which may affect this trend to reduction are discussed.

MeSH terms

  • Antitubercular Agents / pharmacology*
  • Drug Resistance, Microbial
  • England
  • Humans
  • India / ethnology
  • Isoniazid / pharmacology
  • Longitudinal Studies
  • Mycobacterium tuberculosis / drug effects*
  • Tuberculosis / ethnology
  • Tuberculosis / microbiology*

Substances

  • Antitubercular Agents
  • Isoniazid