[How do chromosomes attach to synaptonemal complexes?]

Genetika. 2010 Oct;46(10):1363-6.
[Article in Russian]

Abstract

Fluorochrome-labeled oligonucleotides (n = 44) corresponding to mouse genome repetitive sequences were hybridized in situ with pachytene nuclei of mouse spermatocytes. Signals of the repetitive sequences MaLR, MER, and (GT)22 were found to be dispersed through chromatin, and signals of BI 1 repeats and minisatellites were mostly attached to synaptonemal complexes immunostained with anti-SYCP3 antibodies. These results suggest that B 1 repeats and minisatellites are candidates for sequences anchoring chromatin to synaptonemal complexes.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chromatin / genetics
  • Chromatin / metabolism*
  • Chromosomes, Mammalian / metabolism*
  • In Situ Hybridization, Fluorescence
  • Male
  • Mice
  • Minisatellite Repeats / physiology
  • Pachytene Stage / physiology*
  • Spermatocytes / metabolism*
  • Synaptonemal Complex / metabolism*

Substances

  • Chromatin