Anomalous origin of left coronary artery from pulmonary artery in older children and adults: direct aortic implantation

Ann Thorac Surg. 2011 Feb;91(2):549-53. doi: 10.1016/j.athoracsur.2010.08.032.


Background: Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) presents rarely in adulthood and is treated by different surgical techniques with varying results. This study was undertaken to evaluate the feasibility of reestablishment of a dual coronary system in older children and adults with emphasis on direct aortic implantation.

Methods: From 2002 to 2010, 10 patients aged 10 to 51 years (median age, 24 years) underwent surgical correction of ALCAPA. Median weight was 44.5 kg. All the patients except 2 were symptomatic. Two patients were in atrial fibrillation. Eight patients had varying degrees of mitral regurgitation, which was severe in 2. In all patients, the left coronary artery was arising from the facing sinus of the pulmonary artery. Direct left main coronary implantation into the aorta was feasible in all patients. Mitral valve replacement was done in 4 patients.

Results: At a median follow-up of 5.5 years there was no new angina or infarction. One patient died 3 months postsurgery due to intracerebral bleed. Echocardiography demonstrated normal antegrade flow in the transferred left coronary artery, with 2 patients having persistent moderate mitral regurgitation. Coronary angiography done on follow-up in one patient revealed a patent transferred left coronary artery with distal development of new atherosclerotic lesion.

Conclusions: Direct reimplantation of the ALCAPA is considered technically more difficult and hazardous in adults. With increased experience with coronary transfer technique, direct aortic implantation is feasible in adult cases. This provides a more physiologic correction and reestablishment of a dual coronary system with a better outcome.

Publication types

  • Evaluation Study

MeSH terms

  • Adolescent
  • Adult
  • Atrial Fibrillation / etiology
  • Child
  • Coronary Angiography
  • Coronary Vessel Anomalies / diagnostic imaging
  • Coronary Vessel Anomalies / surgery*
  • Coronary Vessels / surgery*
  • Echocardiography
  • Feasibility Studies
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Mitral Valve Insufficiency / etiology
  • Postoperative Complications / etiology
  • Postoperative Complications / mortality
  • Pulmonary Artery / abnormalities*
  • Pulmonary Artery / diagnostic imaging
  • Pulmonary Artery / surgery*
  • Retrospective Studies
  • Survival Rate
  • Vascular Surgical Procedures / adverse effects
  • Vascular Surgical Procedures / methods*
  • Young Adult