Protein dynamics: Moore's law in molecular biology
- PMID: 21256436
- DOI: 10.1016/j.cub.2010.11.062
Protein dynamics: Moore's law in molecular biology
Abstract
The millisecond barrier has been broken in molecular dynamics simulations of proteins. Such simulations are increasingly revealing the inner workings of biological systems by generating atomic-level descriptions of their behaviour that make testable predictions about key molecular processes.
Copyright © 2011 Elsevier Ltd. All rights reserved.
Similar articles
-
Long-timescale molecular dynamics simulations of protein structure and function.Curr Opin Struct Biol. 2009 Apr;19(2):120-7. doi: 10.1016/j.sbi.2009.03.004. Epub 2009 Apr 8. Curr Opin Struct Biol. 2009. PMID: 19361980 Review.
-
Molecular simulations of protein dynamics: new windows on mechanisms in biology.EMBO Rep. 2008 Feb;9(2):144-50. doi: 10.1038/sj.embor.7401160. EMBO Rep. 2008. PMID: 18246106 Free PMC article. Review.
-
Long timescale simulations.Curr Opin Struct Biol. 2000 Apr;10(2):160-4. doi: 10.1016/s0959-440x(00)00062-2. Curr Opin Struct Biol. 2000. PMID: 10753819 Review.
-
Biomolecular simulation: a computational microscope for molecular biology.Annu Rev Biophys. 2012;41:429-52. doi: 10.1146/annurev-biophys-042910-155245. Annu Rev Biophys. 2012. PMID: 22577825 Review.
-
Macromolecular crowding: chemistry and physics meet biology (Ascona, Switzerland, 10-14 June 2012).Phys Biol. 2013 Aug;10(4):040301. doi: 10.1088/1478-3975/10/4/040301. Epub 2013 Aug 2. Phys Biol. 2013. PMID: 23912807
Cited by
-
Mathematics's role in the grand challenge of deciphering the molecular basis of life.Front Mol Biosci. 2014 Mar 27;1:2. doi: 10.3389/fmolb.2014.00002. eCollection 2014. Front Mol Biosci. 2014. PMID: 25988143 Free PMC article. No abstract available.
-
A Structure Independent Molecular Fragment Interfuse Model for Mesoscale Dissipative Particle Dynamics Simulation of Peptides.ACS Omega. 2024 Apr 12;9(16):18001-18022. doi: 10.1021/acsomega.3c09534. eCollection 2024 Apr 23. ACS Omega. 2024. PMID: 38680324 Free PMC article.
-
Protein dynamics via computational microscope.World J Methodol. 2012 Dec 26;2(6):42-9. doi: 10.5662/wjm.v2.i6.42. eCollection 2012 Dec 26. World J Methodol. 2012. PMID: 25237616 Free PMC article. Review.
-
How round is a protein? Exploring protein structures for globularity using conformal mapping.Front Mol Biosci. 2014 Dec 9;1:26. doi: 10.3389/fmolb.2014.00026. eCollection 2014. Front Mol Biosci. 2014. PMID: 25988167 Free PMC article.
-
The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage.Elife. 2017 Apr 13;6:e23872. doi: 10.7554/eLife.23872. Elife. 2017. PMID: 28406400 Free PMC article.
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
