Visualization of Microvasculature by Dual-Beam Phase-Resolved Doppler Optical Coherence Tomography

Opt Express. 2011 Jan 17;19(2):1217-27. doi: 10.1364/OE.19.001217.

Abstract

We present a dual-beam Doppler optical coherence tomography system for visualizing the microvasculature within the retina. The sample arm beams from two identical spectral domain optical coherence tomography (SD-OCT) systems are combined such that there is a small horizontal offset between them at the retina. Thereby we record two tomograms which are slightly separated in time. Phase-resolved Doppler analysis is performed between these two data sets. This system allows blood capillary imaging with high flow sensitivity and variable velocity range. To demonstrate the performance of our system we present images of the microvascular network around the fovea and around the optic nerve head of the human eye.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Equipment Design
  • Equipment Failure Analysis
  • Humans
  • Image Enhancement / instrumentation*
  • Image Enhancement / methods
  • Microvessels / cytology*
  • Retinal Vessels / anatomy & histology*
  • Retinoscopes*
  • Tomography, Optical Coherence / instrumentation*
  • Tomography, Optical Coherence / methods*