Superior mesenteric artery syndrome complicating dialysis patients with peritoneal failure--report of 3 cases

Clin Nephrol. 2011 Feb;75 Suppl 1:37-41. doi: 10.5414/cnp75037.

Abstract

We report 3 cases of superior mesenteric artery syndrome in patients previously on maintenance peritoneal dialysis converted to hemodialysis after peritoneal failure. All 3 patients presented with repeated vomiting and severe malnutrition. It is postulated that complications arising from peritoneal dialysis such as peritoneal sclerosis, adhesions and collections after CAPD peritonitis may be important contributing factors for the SMA syndrome in these 3 patients. All of them succumbed within six months of diagnosis. The first 2 patients received gastrointestinal bypass surgery and died post-operatively due to impaired wound healing and nosocomial sepsis. The 3rd patient was treated conservatively with nasoduodenal feeding but succumbed to aspiration pneumonia. It is postulated that complications arising from peritoneal dialysis including peritoneal sclerosis, adhesions and collections after CAPD peritonitis may contribute to the SMA syndrome in these patients. Our experience suggests that SMA syndrome in end-stage renal disease patients is associated with high surgical morbidity and mortality possibly related to their poor pre-morbid condition and pre-existing malnutrition. Aggressive parenteral nutrition should be considered to build up the general status before proceeding to surgical intervention.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Barium Sulfate
  • Contrast Media
  • Cross Infection / etiology
  • Fatal Outcome
  • Female
  • Gastric Bypass / adverse effects
  • Humans
  • Kidney Failure, Chronic / therapy*
  • Male
  • Malnutrition / etiology
  • Middle Aged
  • Parenteral Nutrition, Total / adverse effects
  • Peritoneal Dialysis*
  • Pneumonia, Aspiration / etiology
  • Renal Dialysis / adverse effects*
  • Sepsis / etiology
  • Severity of Illness Index
  • Superior Mesenteric Artery Syndrome / diagnostic imaging
  • Superior Mesenteric Artery Syndrome / etiology*
  • Superior Mesenteric Artery Syndrome / therapy
  • Tomography, X-Ray Computed
  • Treatment Failure
  • Vomiting / etiology
  • Wound Healing

Substances

  • Contrast Media
  • Barium Sulfate